Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50036115
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi:  0.230nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  6.10nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005840(CHEMBL14923 | 4-Amino-5-chloro-N-(hexahydro-pyrrol...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005840(CHEMBL14923 | 4-Amino-5-chloro-N-(hexahydro-pyrrol...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005838(CHEMBL36005 | (exo) 4-Amino-5-chloro-2-ethoxy-N-(h...)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  30nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005841((exo) 4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-y...)
Affinity DataKi:  66nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005839(CHEMBL35180 | (exo) 4-Amino-5-chloro-2-ethoxy-N-(h...)
Affinity DataKi:  99nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005839(CHEMBL35180 | (exo) 4-Amino-5-chloro-2-ethoxy-N-(h...)
Affinity DataKi:  99nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005837(CHEMBL37544 | (endo) 4-Amino-5-chloro-N-(hexahydro...)
Affinity DataKi:  104nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005837(CHEMBL37544 | (endo) 4-Amino-5-chloro-N-(hexahydro...)
Affinity DataKi:  104nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  113nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  134nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataKi:  152nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005842(CHEMBL287237 | (exo) N-(Hexahydro-pyrrolizin-1-yl)...)
Affinity DataKi: >200nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  227nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  240nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  390nMAssay Description:The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain corticesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi:  415nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  1.70E+3nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi:  4.50E+3nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain corticesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]domperidone binding to dopamine receptor D2 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50031475(4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chlor...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50368604(CHEMBL1907770)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
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