Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50015946
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162755((S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-te...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of 2(S)-(4-125I-benzenesulphonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162756((3S,7R)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of 2(S)-(4-125I-benzenesulphonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162757((3S,7S)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of 2(S)-(4-125I-benzenesulphonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153030((S)-3-(6-Methoxy-pyridin-3-yl)-9-(5,6,7,8-tetrahyd...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of 2(S)-(4-125I-benzenesulphonylamino)-3-4-[2-(5,6,7,8-tetrahydro- [1,8]naphthyridin-2-yl)-ethyl]-benzoylamino-propionic acid binding to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162755((S)-3-(6-Methoxy-pyridin-3-yl)-7-oxo-9-(5,6,7,8-te...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of alphaIIb-beta3 integrin mediated platelet aggregation (PLAGGIN15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162756((3S,7R)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of alphaIIb-beta3 integrin mediated platelet aggregation (PLAGGIN15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162757((3S,7S)-7-Hydroxy-3-(6-methoxy-pyridin-3-yl)-9-(5,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of alphaIIb-beta3 integrin mediated platelet aggregation (PLAGGIN15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed