Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50037390
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: 9nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 13nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 25nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: 33nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 38nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 48nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166816(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 80nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166827(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 112nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166825(3-(2-Ethoxy-phenyl)-5-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50: 116nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166819(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: 146nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 184nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: 204nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: 275nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: 289nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166830(3-(2-Ethoxy-phenyl)-6-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50: 381nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 455nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166816(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 472nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 561nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166826(3-(2-Ethoxy-phenyl)-5-ethyl-2H-2,4,4b,9-tetraaza-f...)
Affinity DataIC50: 634nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 693nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166829(6-Bromo-3-(2-ethoxy-phenyl)-5-methyl-2H-2,4,4b,9-t...)
Affinity DataIC50: 710nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166837(3-(2-Ethoxy-phenyl)-7-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50: 849nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166819(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: 860nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50370451(CHEMBL554480)
Affinity DataIC50: 878nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166832(3-(2-Ethoxy-phenyl)-8-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166827(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166834(3-(2-Ethoxy-phenyl)-5-pyrrolidin-1-ylmethyl-2H-2,4...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166836(3-(2-Ethoxy-phenyl)-5-(4-methyl-piperazin-1-ylmeth...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166833(6,8-Dibromo-3-(2-ethoxy-phenyl)-5-methyl-2H-2,4,4b...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166828(6-Bromo-3-(2-ethoxy-phenyl)-2H-2,4,4b,9-tetraaza-f...)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166831(3-(2-Ethoxy-phenyl)-1-oxo-1,2-dihydro-2,4,4b,9-tet...)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166838(3-(2-Ethoxy-phenyl)-5-methyl-1-oxo-1,2-dihydro-2,4...)
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50370451(CHEMBL554480)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166835(3-(2-Ethoxy-phenyl)-2H-2,4,4b,9-tetraaza-fluoren-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed