Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 1335
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Chinese Academy of Sciences

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 200nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Chinese Academy of Sciences

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 350nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Chinese Academy of Sciences

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.10E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Chinese Academy of Sciences

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 2.20E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Chinese Academy of Sciences

LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 4.50E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Chinese Academy of Sciences

LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 4.50E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Rat)
Chinese Academy of Sciences

LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Chinese Academy of Sciences

LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Chinese Academy of Sciences

LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 2.00E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Chinese Academy of Sciences

LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 2.50E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Chinese Academy of Sciences

LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 2.50E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 2.50E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Chinese Academy of Sciences

LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 7.00E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Chinese Academy of Sciences

LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 1.00E+6nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Rat)
Chinese Academy of Sciences

LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 1.00E+6nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Rat)
Chinese Academy of Sciences

LigandPNGBDBM10910(R-2-(6-Benzyloxy-9-isopropyl-9H-purin-2-yl-amino)-...)
Affinity DataIC50: 1.00E+6nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed
LigandPNGBDBM10909(R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-...)
Affinity DataIC50: 1.00E+6nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMed