Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50016579
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170947(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170945(2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170949(2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170943(Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170950(4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170944(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170948(2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170946(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170942(2-Phenyl-2H-pyrazolo[4,3-c]quinoline | CHEMBL19011...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170951(2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 100 nM-NECA stimulation of cAMP levels in human adenosine A2b receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170946(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170948(2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170949(2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170944(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one...)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi:  34nMAssay Description:Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170946(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataKi:  42nMAssay Description:Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170951(2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170944(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one...)
Affinity DataKi:  55nMAssay Description:Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170943(Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170945(2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quin...)
Affinity DataKi:  157nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170950(4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...)
Affinity DataKi:  166nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170942(2-Phenyl-2H-pyrazolo[4,3-c]quinoline | CHEMBL19011...)
Affinity DataKi:  212nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170947(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...)
Affinity DataKi:  220nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170944(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170950(4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170948(2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170945(2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quin...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170947(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170949(2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170951(2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170946(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170941(2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-on...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170951(2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170943(Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170949(2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170944(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170950(4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline | C...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170942(2-Phenyl-2H-pyrazolo[4,3-c]quinoline | CHEMBL19011...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170948(2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qui...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170947(2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-th...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170946(2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]qu...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170945(2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quin...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170943(Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170942(2-Phenyl-2H-pyrazolo[4,3-c]quinoline | CHEMBL19011...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2a receptor expressed in CHO cells; (n=3 - 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed