Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50037524
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.0940nMAssay Description:Binding affinity for human fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132714((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenesulfonyl f...)
Affinity DataIC50: 0.100nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for rat fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171297((5Z,8Z,11Z,14Z)-1-Oxazolo[4,5-b]pyridin-2-yl-icosa...)
Affinity DataKi:  1nMAssay Description:Binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50069273((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataIC50: 2.10nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50100865((Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-o...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132713(Methyl arachidonoyl fluorophophonate | methyl -ico...)
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=1-3 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132716(methyl dodecylphosphonofluoridoate | CHEMBL113263)
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171290(SR 147778 | CHEMBL189676 | 5-(4-Bromo-phenyl)-1-(2...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]CP-55940 binding to human cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171287(Octadecanesulfonyl fluoride | CHEMBL191481)
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171293((6Z,9Z,12Z,15Z)-1-Diazo-henicosa-6,9,12,15-tetraen...)
Affinity DataIC50: 6nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171295((Z)-2-Methyl-1-oxazolo[4,5-b]pyridin-2-yl-octadec-...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataKi:  9.90nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171292(Hexadecanoic acid isopropylamide | CHEMBL32827)
Affinity DataIC50: 13nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171296(HU-310 | 2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetrae...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50073987(1,1,1-trifluoro-9-phenylnonan-2-one | 1,1,1-Triflu...)
Affinity DataKi:  25nMAssay Description:Binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM85675(CHEMBL321585 | Anandamide + PMSF)
Affinity DataKi:  34nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM22988(Arachidonoyl ethanolamide | Arachidonoylethanolami...)
Affinity DataKi:  50nMAssay Description:Binding affinity for human cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50056457((8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-8,11,14-trien...)
Affinity DataKi:  53nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM22988(Arachidonoyl ethanolamide | Arachidonoylethanolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50073986(1,1,1-trifluoro-8-(4-heptylphenyl)-2-octanone | 1,...)
Affinity DataKi:  96nMAssay Description:Apparent binding affinity for fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM20462(Arachidonoyl dopamine | CHEMBL138921 | (5Z,8Z,11Z,...)
Affinity DataKi:  250nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132714((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenesulfonyl f...)
Affinity DataIC50: 304nMAssay Description:Inhibition of [3H]CP-55940 binding to mouse Cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171290(SR 147778 | CHEMBL189676 | 5-(4-Bromo-phenyl)-1-(2...)
Affinity DataKi:  442nMAssay Description:Inhibition of [3H]CP-55940 binding to human cannabinoid receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50046268(6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tet...)
Affinity DataIC50: 800nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1/2(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50069269(4-Bromo-3-oxo-butyric acid (R)-1-methyl-heptyl est...)
Affinity DataKi:  800nMAssay Description:Binding affinity for Cannabinoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM23028((9Z)-octadec-9-enamide | Oleamide | Oleylamide | C...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171285((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50069269(4-Bromo-3-oxo-butyric acid (R)-1-methyl-heptyl est...)
Affinity DataIC50: 2.60E+3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50059523(Arachidonyltrifluoromethane | (6Z,9Z,12Z,15Z)-1,1,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of fatty acid amide hydrolase; range =. 23-3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171299(N-pentadecylcyclohexanecarboxamide | Cyclohexaneca...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory concentration against N-palmitoylethanolamine acid amidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50056486(((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoylamino)-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of fatty acid amide hydrolase; range = 4.1-7 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171288(Acetic acid pentadecylcarbamoylmethyl ester | CHEM...)
Affinity DataIC50: 8.00E+3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171298(Hexadecanoylamino-acetic acid methyl ester | CHEMB...)
Affinity DataIC50: 1.00E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM22987(CHEMBL191534 | Arachidonylserotonin | (5Z,8Z,11Z,1...)
Affinity DataIC50: 1.20E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 1.30E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50096882((5Z,9Z,12Z)-Octadeca-5,9,12-trienoic acid [2-(3,4-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171291(cyclohexyl palmitate | Hexadecanoic acid cyclohexy...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against N-palmitoylethanolamine acid amidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50128913((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory concentration against monoacylglycerol lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50128913((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171294(CHEMBL138543 | Propionic acid hexadecyl ester | HE...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory concentration against N-palmitoylethanolamine acid amidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50058046(propofol | CHEMBL526)
Affinity DataIC50: 5.20E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171286(N-(3-hydroxy-propionyl)pentadecanamide | 3-Hydroxy...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory concentration against N-palmitoylethanolamine acid amidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM23028((9Z)-octadec-9-enamide | Oleamide | Oleylamide | C...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of fatty acid amide hydrolase; range = 22-68 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed