Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 2098
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16839((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16843((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16855((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 2nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16852((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 3nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16839((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16845((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16853((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 4nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16833((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16858((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 6nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16858((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 6nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16855((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 7nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16843((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 7nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16841((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16847((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16856((2S)-2-{[(3S)-2-[(benzyloxy)carbonyl]-2-azabicyclo...)
Affinity DataIC50: 9nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16857((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 9nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16836((2S)-2-{[(3S)-2-(3-{[(tert-butoxy)carbonyl]amino}p...)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16846((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16857((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 10nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16844((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16840((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16833((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 15nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16867(CHEMBL156019 | (2S)-2-{[(3S)-2-(benzenesulfonyl)-2...)
Affinity DataIC50: 19nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16851((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 20nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16866((2S)-2-[(3S)-2-azabicyclo[2.2.2]octan-3-ylformamid...)
Affinity DataIC50: 23nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16848((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16838((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16854((2S)-2-{[(3S)-2-[3-(4-chlorophenyl)propanoyl]-2-az...)
Affinity DataIC50: 24nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16856((2S)-2-{[(3S)-2-[(benzyloxy)carbonyl]-2-azabicyclo...)
Affinity DataIC50: 24nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16850((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 25nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16834((2S)-2-{[(3S)-2-(3-cyclopentylpropanoyl)-2-azabicy...)
Affinity DataIC50: 27nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16834((2S)-2-{[(3S)-2-(3-cyclopentylpropanoyl)-2-azabicy...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16837((2S)-2-{[(3S)-2-(3-aminopropanoyl)-2-azabicyclo[2....)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16836((2S)-2-{[(3S)-2-(3-{[(tert-butoxy)carbonyl]amino}p...)
Affinity DataIC50: 30nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16844((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 30nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16846((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 30nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16854((2S)-2-{[(3S)-2-[3-(4-chlorophenyl)propanoyl]-2-az...)
Affinity DataIC50: 31nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16850((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 32nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16852((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 32nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16861((2S)-2-{[(3S)-2-(benzylcarbamoyl)-2-azabicyclo[2.2...)
Affinity DataIC50: 38nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16845((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 41nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16835((2S)-2-{[(3S)-2-(4-cyclohexylbutanoyl)-2-azabicycl...)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16866((2S)-2-[(3S)-2-azabicyclo[2.2.2]octan-3-ylformamid...)
Affinity DataIC50: 45nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16853((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 46nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16840((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 47nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16862((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 47nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16837((2S)-2-{[(3S)-2-(3-aminopropanoyl)-2-azabicyclo[2....)
Affinity DataIC50: 60nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16851((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 62nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16863((2S)-3-{4-[(3,5-dichloropyridine-4-)amido]phenyl}-...)
Affinity DataIC50: 62nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM16861((2S)-2-{[(3S)-2-(benzylcarbamoyl)-2-azabicyclo[2.2...)
Affinity DataIC50: 72nMT: 2°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2007
Entry Details Article
PubMed
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