Compile Data Set for Download or QSAR
Report error Found 114 Enz. Inhib. hit(s) with all data for entry = 50016705
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172262(1-(5-Chloro-3-methyl-pyrazol-1-ylmethanesulfonyl)-...)
Affinity DataEC50:  89.5nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172281(1-(2-Fluoro-benzenesulfonyl)-3-(1,2,5,6-tetrahydro...)
Affinity DataEC50:  51nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172278(1-(5-Bromo-thiophene-2-sulfonyl)-3-((R)-1-methyl-p...)
Affinity DataEC50:  103nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172298(1-(3-Fluoro-benzenesulfonyl)-3-(1,2,5,6-tetrahydro...)
Affinity DataEC50:  270nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172302(1-(3,4-Difluoro-benzenesulfonyl)-3-piperidin-3-yl-...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172313(1-(5-Chloro-thiophene-2-sulfonyl)-3-piperidin-3-yl...)
Affinity DataEC50:  58.5nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172296(1-Benzenesulfonyl-3-(1,2,5,6-tetrahydro-pyridin-3-...)
Affinity DataEC50:  159nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172301(1-(4-Fluoro-benzenesulfonyl)-3-(1,2,5,6-tetrahydro...)
Affinity DataEC50:  345nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169599(CHEMBL194307 | CHEMBL187865 | 1-Benzenesulfonyl-3-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172267(1-(3,4-Dimethoxy-benzenesulfonyl)-3-((S)-1-methyl-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172292(1-(5-Chloro-thiophene-2-sulfonyl)-3-((S)-1-methyl-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172253(1-(4-Methoxy-benzenesulfonyl)-3-piperidin-3-yl-1H-...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172282(1-(3,4-Dichloro-benzenesulfonyl)-3-((S)-1-methyl-p...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172268(4-(3-(S)-1-Pyrrolidin-2-ylmethyl-indole-1-sulfonyl...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172257(1-(4-Chloro-benzenesulfonyl)-3-((S)-1-methyl-pyrro...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172308(1-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonyl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172258(4-[3-(1-Methyl-pyrrolidin-3-yl)-indole-1-sulfonyl]...)
Affinity DataIC50: 15.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172317(3-(1-Benzyl-pyrrolidin-3-yl)-1-(2-bromo-benzenesul...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172284(4-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-indole-1...)
Affinity DataIC50: 24.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172283(4-[3-(1-Benzyl-pyrrolidin-3-yl)-indole-1-sulfonyl]...)
Affinity DataIC50: 25nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172305(1-(4-Iodo-benzenesulfonyl)-3-(1-methyl-pyrrolidin-...)
Affinity DataIC50: 43.6nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172320(1-(4-Iodo-benzenesulfonyl)-3-((S)-1-methyl-pyrroli...)
Affinity DataIC50: 49.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172286(1-(4-Fluoro-benzenesulfonyl)-3-(1-methyl-pyrrolidi...)
Affinity DataIC50: 52.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34147(CHEMBL425196 | pyrrolidinylindole, 6)
Affinity DataIC50: 53.3nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172270(3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1-(toluene-...)
Affinity DataIC50: 56.3nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172279(3-(1-Benzyl-pyrrolidin-3-yl)-1-(3,4-dichloro-benze...)
Affinity DataIC50: 61nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172293(1-(2-Bromo-benzenesulfonyl)-3-((S)-1-methyl-pyrrol...)
Affinity DataIC50: 76.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169601(CHEMBL196102 | CHEMBL373107 | 1-Benzenesulfonyl-3-...)
Affinity DataIC50: 81.4nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172255(1-(4-Chloro-benzenesulfonyl)-3-(1-methyl-pyrrolidi...)
Affinity DataIC50: 85.5nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172297(1-(3-Chloro-benzenesulfonyl)-3-((S)-1-methyl-pyrro...)
Affinity DataIC50: 96.2nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172260(1-(3,4-Dimethoxy-benzenesulfonyl)-3-(1-methyl-pyrr...)
Affinity DataIC50: 96.7nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172271(1-(3,4-Dichloro-benzenesulfonyl)-3-(1-methyl-pyrro...)
Affinity DataIC50: 107nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172291(3-(1-Benzyl-pyrrolidin-3-yl)-1-(5-bromo-thiophene-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172311(5-[3-(1-Benzyl-pyrrolidin-3-yl)-indole-1-sulfonyl]...)
Affinity DataIC50: 110nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172261(1-(5-Bromo-thiophene-2-sulfonyl)-3-((S)-1-methyl-p...)
Affinity DataIC50: 112nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172264(3-(1-Benzyl-pyrrolidin-3-yl)-1-(toluene-4-sulfonyl...)
Affinity DataIC50: 123nMAssay Description:Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172255(1-(4-Chloro-benzenesulfonyl)-3-(1-methyl-pyrrolidi...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172258(4-[3-(1-Methyl-pyrrolidin-3-yl)-indole-1-sulfonyl]...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34147(CHEMBL425196 | pyrrolidinylindole, 6)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172283(4-[3-(1-Benzyl-pyrrolidin-3-yl)-indole-1-sulfonyl]...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172305(1-(4-Iodo-benzenesulfonyl)-3-(1-methyl-pyrrolidin-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172310((1-Benzenesulfonyl-5-methoxy-1H-indol-3-ylmethyl)-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158041(1-Benzenesulfonyl-3-(1,2,3,6-tetrahydro-pyridin-4-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172286(1-(4-Fluoro-benzenesulfonyl)-3-(1-methyl-pyrrolidi...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50172314(1-(3-Chloro-benzenesulfonyl)-3-piperidin-3-yl-1H-i...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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