Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 1481
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11636(N-[2-(diethylamino)ethyl]-4-[(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  1.40nM ΔG°:  -50.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11634(heterocyclic sulfonamide compound 38 | 2,3,4,5,6-p...)
Affinity DataKi:  1.5nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  5nM ΔG°:  -46.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  5nM ΔG°:  -46.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11637((15S)-15-methyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11636(N-[2-(diethylamino)ethyl]-4-[(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  19nM ΔG°:  -43.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  21nM ΔG°:  -43.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  21nM ΔG°:  -43.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11634(heterocyclic sulfonamide compound 38 | 2,3,4,5,6-p...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11637((15S)-15-methyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  31nM ΔG°:  -42.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  40nM ΔG°:  -41.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  58nM ΔG°:  -40.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed