Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50036007
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50: 12nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50: 46nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50: 49nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006496(CHEMBL304302 | (7-Bromo-6-chloro-4-hydroxy-2-methy...)
Affinity DataIC50: 50nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006500(CHEMBL69938 | (7-Benzyloxy-6-chloro-4-hydroxy-2-me...)
Affinity DataIC50: 60nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006530(CHEMBL69769 | (7-Fluoro-4-hydroxy-2-methyl-6-nitro...)
Affinity DataIC50: 70nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006496(CHEMBL304302 | (7-Bromo-6-chloro-4-hydroxy-2-methy...)
Affinity DataIC50: 70nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006493(CHEMBL70190 | 4-Carboxymethyl-4-hydroxy-2-methyl-c...)
Affinity DataIC50: 70nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006532(CHEMBL69546 | (4-Hydroxy-2-methyl-6-nitro-chroman-...)
Affinity DataIC50: 80nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006533(CHEMBL302804 | (4-Hydroxy-2,7-dimethyl-6-nitro-chr...)
Affinity DataIC50: 90nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006507(CHEMBL68963 | (7-Bromo-6-fluoro-4-hydroxy-2-methyl...)
Affinity DataIC50: 90nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006529(CHEMBL305985 | (6-Chloro-7-ethyl-4-hydroxy-2-methy...)
Affinity DataIC50: 100nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006504(CHEMBL303474 | (7-Chloro-4-hydroxy-2-methyl-6-nitr...)
Affinity DataIC50: 110nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006507(CHEMBL68963 | (7-Bromo-6-fluoro-4-hydroxy-2-methyl...)
Affinity DataIC50: 120nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006509(CHEMBL441254 | (6-Cyano-7-fluoro-4-hydroxy-2-methy...)
Affinity DataIC50: 130nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502(CHEMBL70014 | (-)-(6,7-Dichloro-4-hydroxy-2-methyl...)
Affinity DataIC50: 140nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502(CHEMBL70014 | (-)-(6,7-Dichloro-4-hydroxy-2-methyl...)
Affinity DataIC50: 156nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502(CHEMBL70014 | (-)-(6,7-Dichloro-4-hydroxy-2-methyl...)
Affinity DataIC50: 180nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502(CHEMBL70014 | (-)-(6,7-Dichloro-4-hydroxy-2-methyl...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006513(CHEMBL68992 | (6-Chloro-4-hydroxy-7-methoxy-2-meth...)
Affinity DataIC50: 190nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006506(CHEMBL71701 | (6-Fluoro-4-hydroxy-2-methyl-chroman...)
Affinity DataIC50: 200nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006524(CHEMBL69689 | (6-Chloro-4-hydroxy-2,7-dimethyl-chr...)
Affinity DataIC50: 240nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006498(CHEMBL71820 | (6,7-Difluoro-4-hydroxy-2-methyl-chr...)
Affinity DataIC50: 250nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006506(CHEMBL71701 | (6-Fluoro-4-hydroxy-2-methyl-chroman...)
Affinity DataIC50: 310nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006498(CHEMBL71820 | (6,7-Difluoro-4-hydroxy-2-methyl-chr...)
Affinity DataIC50: 350nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006508(CHEMBL304798 | (2-tert-Butyl-6-fluoro-4-hydroxy-ch...)
Affinity DataIC50: 360nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006519(CHEMBL307121 | (6-Chloro-7-fluoro-4-hydroxy-2-meth...)
Affinity DataIC50: 390nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006534(CHEMBL67264 | (4-Hydroxy-2,2-dimethyl-6-nitro-chro...)
Affinity DataIC50: 400nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006535(CHEMBL421111 | (6-Chloro-4-hydroxy-2-methyl-3,4-di...)
Affinity DataIC50: 400nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006519(CHEMBL307121 | (6-Chloro-7-fluoro-4-hydroxy-2-meth...)
Affinity DataIC50: 410nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006503(CHEMBL68091 | (6-Fluoro-4-hydroxy-2-isopropyl-chro...)
Affinity DataIC50: 570nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006523(CHEMBL68635 | (6-Fluoro-4-hydroxy-chroman-4-yl)-ac...)
Affinity DataIC50: 600nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006488(CHEMBL306591 | (2-Ethyl-6-fluoro-4-hydroxy-chroman...)
Affinity DataIC50: 620nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006536(CHEMBL69646 | (6-Acetyl-4-hydroxy-2-methyl-chroman...)
Affinity DataIC50: 650nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006510(CHEMBL65967 | (7,8-Dichloro-4-hydroxy-2-methyl-chr...)
Affinity DataIC50: 780nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006512(CHEMBL69708 | (6-Chloro-4-hydroxy-2-methyl-chroman...)
Affinity DataIC50: 820nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006538(CHEMBL69586 | (6-Fluoro-4-hydroxy-2,3-dimethyl-chr...)
Affinity DataIC50: 910nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006491(CHEMBL71562 | (6-Fluoro-4-hydroxy-2-propyl-chroman...)
Affinity DataIC50: 970nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006521(CHEMBL303952 | (6,8-Dichloro-4-hydroxy-2-methyl-ch...)
Affinity DataIC50: 1.00E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006499(CHEMBL306687 | (6-Fluoro-4-hydroxy-2-phenethyl-chr...)
Affinity DataIC50: 1.14E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006511(CHEMBL66326 | (6-Chloro-4-hydroxy-2,8-dimethyl-chr...)
Affinity DataIC50: 1.18E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368324(CHEMBL1744091)
Affinity DataIC50: 1.39E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006492(CHEMBL308882 | (4-Hydroxy-2,5-dimethyl-5-nitro-3,4...)
Affinity DataIC50: 1.63E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006520(CHEMBL69870 | (5,6-Dichloro-4-hydroxy-2-methyl-chr...)
Affinity DataIC50: 1.63E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006531(CHEMBL304945 | (6-Bromo-4-hydroxy-2-methyl-chroman...)
Affinity DataIC50: 1.67E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006527(CHEMBL414676 | (6,7-Dichloro-4-hydroxy-2,2-dimethy...)
Affinity DataIC50: 1.86E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006517(CHEMBL67751 | (7-Fluoro-9-hydroxy-1,2,3,3a,9,9a-he...)
Affinity DataIC50: 1.92E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006540(CHEMBL304797 | (6-Fluoro-4-hydroxy-2-phenyl-chroma...)
Affinity DataIC50: 2.67E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006514(CHEMBL305986 | (7-Chloro-4-hydroxy-2-methyl-chroma...)
Affinity DataIC50: 3.32E+3nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
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