Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50016793
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173870(3-Benzyloxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-be...)
Affinity DataKi:  2.80nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173865(3-Butoxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benzo...)
Affinity DataKi:  3.10nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173865(3-Butoxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benzo...)
Affinity DataKi:  6.30nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173871(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi:  7.40nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173862(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  7.5nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173870(3-Benzyloxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-be...)
Affinity DataKi:  7.90nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173867(3-Methyl-1,1-dioxo-1H-1lambda*6*-benzo[b]thiophene...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173864(1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[b]thioph...)
Affinity DataKi:  8.80nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173864(1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[b]thioph...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173871(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173867(3-Methyl-1,1-dioxo-1H-1lambda*6*-benzo[b]thiophene...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173862(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  27nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  34nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  38nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  50nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173862(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  63nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173864(1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[b]thioph...)
Affinity DataKi:  72nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173871(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi:  75nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173869(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  76nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173867(3-Methyl-1,1-dioxo-1H-1lambda*6*-benzo[b]thiophene...)
Affinity DataKi:  85nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173865(3-Butoxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benzo...)
Affinity DataKi:  104nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173870(3-Benzyloxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-be...)
Affinity DataKi:  138nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173868(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  362nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173868(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  436nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173869(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  475nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173869(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  493nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173868(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi:  530nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  780nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  900nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173863(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173866(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173863(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173863(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173866(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50173866(1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-5-sulfon...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against catalytic domain of human cloned Carbonic anhydrase IX by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed