Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1950
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15361(CHEMBL414883 | Monorden | (4R,6R,8R,9Z,11E)-16-chl...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15410(N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]th...)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15359(17AAG | Tanespimycin | GLD-36 | (4E,6Z,8S,9S,10E,1...)
Affinity DataIC50: 1.27E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15404(4-chloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)...)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15402(N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]be...)
Affinity DataIC50: 3.30E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15405(4-bromo-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)p...)
Affinity DataIC50: 6.10E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15406(4-ethyl-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)p...)
Affinity DataIC50: 6.60E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15403(4-fluoro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)...)
Affinity DataIC50: 8.80E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15409(N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]-2...)
Affinity DataIC50: 1.52E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15407(4-tert-butyl-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50: 2.64E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed