Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50037648
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50039251(CHEMBL1027 | Gabitril | 1-[4,4-Bis-(3-methyl-4,5-d...)
Affinity DataIC50: 280nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175792((R)-1-[4,4-bis(3-(phenoxymethyl)-2-thienyl)-3-bute...)
Affinity DataIC50: 340nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175796(1-(4,4-bis(3-(phenoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50: 650nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175799((R)-1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-y...)
Affinity DataIC50: 680nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175783((R)-1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50: 840nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175790(1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50: 940nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175784(1-(4,4-bis(3-(cyclohexyloxymethyl)thiophen-2-yl)bu...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175791(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperi...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175786(1-(4,4-bis(3-(phenoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175788((R)-1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175793(1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)but-3-...)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175800((R)-1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)b...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175795(1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175785(1-(4,4-bis(3-(benzyloxymethyl)thiophen-2-yl)but-3-...)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175802((R)-1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiop...)
Affinity DataIC50: 6.63E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50020883(CHEMBL77575 | (R)-Piperidine-3-carboxylic acid | N...)
Affinity DataIC50: 8.15E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175789(1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiophen-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175794(1-(4,4-bis(3-((naphthalen-1-yloxy)methyl)thiophen-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175787(1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)but-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175797(1-(4,4-bis(3-(isopropoxymethyl)thiophen-2-yl)but-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175798(1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50175801(1-(4,4-bis(3-(methoxymethyl)thiophen-2-yl)but-3-en...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed