Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 1198
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9914(3-[(R)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9915(3-[(S)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9916(CHEMBL522917 | 3-[(R)-(4-bromophenyl)(1H-imidazol-...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9917(3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9918(CHEMBL225079 | 4-[(R)-1H-imidazol-1-yl(4-oxo-4H-ch...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9919(CHEMBL451201 | 4-[(S)-1H-imidazol-1-yl(4-oxo-4H-ch...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9914(3-[(R)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9916(CHEMBL522917 | 3-[(R)-(4-bromophenyl)(1H-imidazol-...)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9915(3-[(S)-1H-imidazol-1-yl(4-nitrophenyl)methyl]-4H-c...)
Affinity DataIC50: 96nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9918(CHEMBL225079 | 4-[(R)-1H-imidazol-1-yl(4-oxo-4H-ch...)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9917(3-[(S)-(4-bromophenyl)(1H-imidazol-1-yl)methyl]-4H...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

LigandPNGBDBM9919(CHEMBL451201 | 4-[(S)-1H-imidazol-1-yl(4-oxo-4H-ch...)
Affinity DataIC50: 630nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2006
Entry Details Article
PubMed