Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1589
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12407(CHEMBL205877 | 3-chloro-N-[5-({6-methoxy-7-[3-(mor...)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12408(3-chloro-4-fluoro-N-[5-({6-methoxy-7-[3-(morpholin...)
Affinity DataIC50: 0.150nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12405(CHEMBL381724 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12413(CHEMBL204318 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12409(3-bromo-N-[5-({6-methoxy-7-[3-(morpholin-4-yl)prop...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12410(4-ethyl-N-[5-({6-methoxy-7-[3-(morpholin-4-yl)prop...)
Affinity DataIC50: 85nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM14210(N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12403(CHEMBL382590 | N-{4-[(6,7-dimethoxyquinazolin-4-yl...)
Affinity DataIC50: 393nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12406(CHEMBL206266 | N-[2-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50: 629nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12412(CHEMBL203507 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50: 690nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Astrazeneca

LigandPNGBDBM12411(4-(dipropylsulfamoyl)-N-[5-({6-methoxy-7-[3-(morph...)
Affinity DataIC50: 3.90E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMed