Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50017252
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174677((2S,3R,4S,5S,6R)-2-(3-(2-(2,3-dihydrobenzofuran-5-...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179675((2S,3R,4S,5S,6R)-2-(3-(4-ethylbenzyl)-1H-indol-4-y...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179679((2S,3R,4S,5S,6R)-2-(3-(4-(thiophen-3-yl)benzyl)-1H...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179670((2S,3R,4S,5S,6R)-2-(3-(4-(methylthio)benzyl)-1H-in...)
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179671((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179678((2S,3R,4S,5S,6R)-2-(3-Biphenyl-4-ylmethyl-1H-indol...)
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179674((2S,3R,4S,5S,6R)-2-(3-(4-ethoxybenzyl)-1H-indol-4-...)
Affinity DataIC50: 94nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179684((2S,3R,4S,5S,6R)-2-(3-(3-fluoro-4-methylbenzyl)-1H...)
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179682((2S,3R,4S,5S,6R)-2-(3-(4-propylbenzyl)-1H-indol-4-...)
Affinity DataIC50: 119nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179673((2S,3R,4S,5S,6R)-2-(3-(4-methoxybenzyl)-1H-indol-4...)
Affinity DataIC50: 121nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179686((2S,3R,4S,5S,6R)-2-(3-(2-(2,3-dihydrobenzo[b][1,4]...)
Affinity DataIC50: 121nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179685((2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-1H-indol-5-y...)
Affinity DataIC50: 132nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 139nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179672((2S,3R,4S,5S,6R)-2-(3-(4-(pyridin-3-yl)benzyl)-1H-...)
Affinity DataIC50: 143nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179677((2S,3R,4S,5S,6R)-2-(3-(3-fluoro-4-methoxybenzyl)-1...)
Affinity DataIC50: 143nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174677((2S,3R,4S,5S,6R)-2-(3-(2-(2,3-dihydrobenzofuran-5-...)
Affinity DataIC50: 145nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 163nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179688((2S,3R,4S,5S,6R)-2-[3-(2-Fluoro-biphenyl-4-ylmethy...)
Affinity DataIC50: 182nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179676((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(3-(2-(naphth...)
Affinity DataIC50: 201nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179683((2S,3R,4S,5S,6R)-2-(3-(4-ethoxyphenethyl)-1H-indol...)
Affinity DataIC50: 202nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179680((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(3-(naphthale...)
Affinity DataIC50: 293nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179687((2S,3R,4S,5S,6R)-2-(3-(4-chlorobenzyl)-1H-indol-4-...)
Affinity DataIC50: 296nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 611nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179676((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(3-(2-(naphth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179683((2S,3R,4S,5S,6R)-2-(3-(4-ethoxyphenethyl)-1H-indol...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179673((2S,3R,4S,5S,6R)-2-(3-(4-methoxybenzyl)-1H-indol-4...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179681((2S,3R,4S,5S,6R)-2-(3-((2,3-dihydrobenzofuran-6-yl...)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179672((2S,3R,4S,5S,6R)-2-(3-(4-(pyridin-3-yl)benzyl)-1H-...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179675((2S,3R,4S,5S,6R)-2-(3-(4-ethylbenzyl)-1H-indol-4-y...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179679((2S,3R,4S,5S,6R)-2-(3-(4-(thiophen-3-yl)benzyl)-1H...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179670((2S,3R,4S,5S,6R)-2-(3-(4-(methylthio)benzyl)-1H-in...)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179682((2S,3R,4S,5S,6R)-2-(3-(4-propylbenzyl)-1H-indol-4-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179686((2S,3R,4S,5S,6R)-2-(3-(2-(2,3-dihydrobenzo[b][1,4]...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179671((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed