Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50003764
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220060((14-dimethylaminomethyl-6H,13H-pyrazino[1,2-a;4,5-...)
Affinity DataEC50:  1.66E+4nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220060((14-dimethylaminomethyl-6H,13H-pyrazino[1,2-a;4,5-...)
Affinity DataEC50:  447nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50475689(4,4''-Dimethylcaracurinium V Dichloride | Dimethyl...)
Affinity DataEC50:  8.10nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50025037(CHEBI:3382 | Caracurine V)
Affinity DataEC50:  437nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220046(trimethyl({20-[(trimethylazaniumyl)methyl]-3,13-di...)
Affinity DataEC50:  1.12E+4nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045([(20-{[dimethyl(prop-2-en-1-yl)azaniumyl]methyl}-3...)
Affinity DataEC50:  110nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50475690(4,4''-Diallylcaracurinium V Dibromide | Diallylcar...)
Affinity DataEC50:  11nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220046(trimethyl({20-[(trimethylazaniumyl)methyl]-3,13-di...)
Affinity DataEC50:  229nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045([(20-{[dimethyl(prop-2-en-1-yl)azaniumyl]methyl}-3...)
Affinity DataEC50:  2.29E+3nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220046(trimethyl({20-[(trimethylazaniumyl)methyl]-3,13-di...)
Affinity DataKi:  331nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045([(20-{[dimethyl(prop-2-en-1-yl)azaniumyl]methyl}-3...)
Affinity DataKi:  550nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50475690(4,4''-Diallylcaracurinium V Dibromide | Diallylcar...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50475689(4,4''-Dimethylcaracurinium V Dichloride | Dimethyl...)
Affinity DataKi:  5.25E+3nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220060((14-dimethylaminomethyl-6H,13H-pyrazino[1,2-a;4,5-...)
Affinity DataKi:  1.07E+4nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50025037(CHEBI:3382 | Caracurine V)
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed