Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50017278
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180009(7-(2,6-dimethylpyridin-4-yl)-9-ethyl-1-thia-2,4a-d...)
Affinity DataIC50: 200nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 300nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180011(9-ethyl-7-pyridin-4-yl-1-thia-2,4a-diaza-cyclopent...)
Affinity DataIC50: 400nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50045000(CHEMBL9 | (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-pi...)
Affinity DataIC50: 600nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50045000(CHEMBL9 | (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-pi...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180009(7-(2,6-dimethylpyridin-4-yl)-9-ethyl-1-thia-2,4a-d...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180011(9-ethyl-7-pyridin-4-yl-1-thia-2,4a-diaza-cyclopent...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180012(9-ethyl-7-piperazin-1-yl-1-thia-2,4a-diazacyclopen...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180010((rac)-7-(3-dimethylaminopyrrolidin-1-yl)-9-ethyl-1...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli ATCC 25922More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180012(9-ethyl-7-piperazin-1-yl-1-thia-2,4a-diazacyclopen...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50180010((rac)-7-(3-dimethylaminopyrrolidin-1-yl)-9-ethyl-1...)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of topoisomerase 4 decatenation in Staphylococcus aureus ATCC 29213More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed