Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 2803
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24828(N-[2-(1H-indol-3-yl)ethyl][(naphthalen-2-ylmethyl)...)
Affinity DataKi:  1.16E+4nM ΔG°:  -29.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24825((benzylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioa...)
Affinity DataKi:  1.32E+4nM ΔG°:  -29.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24827((benzylsulfanyl)-N-[2-(1H-indol-3-yl)ethyl]carboth...)
Affinity DataKi:  1.72E+4nM ΔG°:  -28.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24830(N-[2-(1H-indol-3-yl)ethyl][(pyridin-4-ylmethyl)sul...)
Affinity DataKi:  2.05E+4nM ΔG°:  -27.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24829(N-[2-(1H-indol-3-yl)ethyl][(pyridin-3-ylmethyl)sul...)
Affinity DataKi:  2.84E+4nM ΔG°:  -27.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24816(N-[3-(1H-indol-3-yl)propyl](methylsulfanyl)carboth...)
Affinity DataKi:  3.40E+4nM ΔG°:  -26.5kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24824(N-(1H-indol-3-ylmethyl)(prop-2-en-1-ylsulfanyl)car...)
Affinity DataKi:  3.70E+4nM ΔG°:  -26.3kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24815(N-[2-(1-benzothiophen-3-yl)ethyl](methylsulfanyl)c...)
Affinity DataKi:  4.10E+4nM ΔG°:  -26.1kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24817(N-(2,3-dihydro-1H-inden-2-yl)(methylsulfanyl)carbo...)
Affinity DataKi:  4.21E+4nM ΔG°:  -26.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24819((methylsulfanyl)-N-(naphthalen-2-ylmethyl)carbothi...)
Affinity DataKi:  4.76E+4nM ΔG°:  -25.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24821((methylsulfanyl)-N-(2-phenylethyl)carbothioamide |...)
Affinity DataKi:  6.24E+4nM ΔG°:  -25.0kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24820(N-benzyl(methylsulfanyl)carbothioamide | Brassinin...)
Affinity DataKi:  7.24E+4nM ΔG°:  -24.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24814(N-[2-(1H-indol-3-yl)ethyl](methylsulfanyl)carbothi...)
Affinity DataKi:  8.25E+4nM ΔG°:  -24.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24813(methyl N-(1H-indol-3-ylmethyl)carbamodithioate | N...)
Affinity DataKi:  9.77E+4nM ΔG°:  -23.8kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24822(N-[2-(4-fluorophenyl)ethyl](methylsulfanyl)carboth...)
Affinity DataKi:  1.49E+5nM ΔG°:  -22.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24818(N-(adamantan-2-yl)(methylsulfanyl)carbothioamide |...)
Affinity DataKi:  1.80E+5nM ΔG°:  -22.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24834(N-(1H-indol-3-ylmethyl)propanethioamide | thioamid...)
Affinity DataKi:  2.02E+5nM ΔG°:  -21.9kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24836(4-(1H-indol-3-ylmethyl)-2-methyl-1,3-thiazole | th...)
Affinity DataKi:  3.29E+5nM ΔG°:  -20.7kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24832(1-[2-(1H-indol-3-yl)ethyl]-3-methylthiourea | thio...)
Affinity DataKi:  3.42E+5nM ΔG°:  -20.6kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24826((hexylsulfanyl)-N-(1H-indol-3-ylmethyl)carbothioam...)
Affinity DataKi:  3.64E+5nM ΔG°:  -20.4kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24823(N-methyl(methylsulfanyl)-N-(2-phenylethyl)carbothi...)
Affinity DataKi:  1.27E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24835(4-(1H-indol-3-ylmethyl)-1,3-thiazole | thiazole, 2...)
Affinity DataKi:  1.29E+6nM ΔG°:  -17.2kJ/molepH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24831(1-(1H-indol-3-ylmethyl)-3-methylthiourea | thioure...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24833(N-(1H-indol-3-ylmethyl)(methylsulfanyl)formamide |...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed