Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 6565
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataIC50: 0.0690nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataIC50: 1nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50232153(CHEMBL257283 | MDL-100907 | MDL 100907 | (1-(4-flu...)
Affinity DataIC50: 1.10nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 1.90nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataIC50: 3nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataIC50: 4.5nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50: 13nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 91nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50: 100nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataIC50: 200nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50232153(CHEMBL257283 | MDL-100907 | MDL 100907 | (1-(4-flu...)
Affinity DataIC50: 540nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50232153(CHEMBL257283 | MDL-100907 | MDL 100907 | (1-(4-flu...)
Affinity DataKi:  0.0300nM ΔG°:  -55.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  0.0460nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.0830nM ΔG°:  -53.5kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.440nM ΔG°:  -49.6kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  0.550nM ΔG°:  -49.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139371(eplivanserin)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.30nM ΔG°:  -47.1kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataKi:  1.60nM ΔG°:  -46.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Acadia Pharmaceuticals

LigandPNGBDBM50232153(CHEMBL257283 | MDL-100907 | MDL 100907 | (1-(4-flu...)
Affinity DataKi:  3.80nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details Article
PubMed