Compile Data Set for Download or QSAR
Report error Found 279 Enz. Inhib. hit(s) with all data for entry = 50037671
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182548(1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182560((1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 11.3nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182573(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182546(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 11.7nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182575(1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-on...)
Affinity DataIC50: 11.8nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataIC50: 12.4nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataKi:  13.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182560((1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 16.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182565(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182560((1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi:  18.1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182564(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-en...)
Affinity DataIC50: 18.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182562(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-o...)
Affinity DataIC50: 18.5nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182575(1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-on...)
Affinity DataIC50: 19.3nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182551(1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50: 19.7nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182546(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  20.1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182573(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182555(pyrovalerone | 1-(4-methylphenyl)-2-pyrrolidin-1-y...)
Affinity DataKi:  21.4nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182547(4-(2-pyrrolidin-1-yl-pentanoyl)benzoic acid methyl...)
Affinity DataIC50: 22.8nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182564(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-en...)
Affinity DataIC50: 24.9nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182555(pyrovalerone | 1-(4-methylphenyl)-2-pyrrolidin-1-y...)
Affinity DataIC50: 28.3nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182562(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-o...)
Affinity DataKi:  28.8nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182579(N-[4-(2-pyrrolidin-1-yl-pentanoyl)phenyl]acetamide...)
Affinity DataKi:  30.2nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182546(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  33.1nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataKi:  33.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182573(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)
Affinity DataKi:  37.8nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182578(1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 39.5nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182564(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-en...)
Affinity DataKi:  39.9nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182546(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 42nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182573(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataIC50: 44.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182546(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50: 46nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 46.5nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataKi:  48.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182549(1-(4-hydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one...)
Affinity DataIC50: 49.7nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182578(1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182548(1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182555(pyrovalerone | 1-(4-methylphenyl)-2-pyrrolidin-1-y...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataIC50: 52.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182572(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pent-4-ene-1-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182562(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-o...)
Affinity DataIC50: 55nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182584(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)
Affinity DataIC50: 56nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182551(1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataKi:  59.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182575(1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-on...)
Affinity DataKi:  61nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182548(1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50: 62.9nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182551(1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
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