Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50017635
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184818(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184822(methyl 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184812(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184817(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184811((R)-1-(2-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184816(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyr...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184808((S)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184813((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184821(N-(3-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-met...)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184809(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184820(methyl 5-methyl-4-(2-methyl-1H-indol-5-yloxy)pyrro...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184814(ethyl 4-(1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][...)
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Mouse)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against Flk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184819(methyl 4-(1H-indol-5-yloxy)pyrrolo[2,1-f][1,2,4]tr...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184810(ethyl 4-(1H-indol-5-yloxy)-5-ethylpyrrolo[2,1-f][1...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184815(ethyl 4-(1H-indol-5-yloxy)-5-isopropylpyrrolo[2,1-...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184812(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184813((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184818(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184821(N-(3-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-met...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184817(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184808((S)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184811((R)-1-(2-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184809(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184813((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against hERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against hERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184809(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against hERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against PKC alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Mouse)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against Flk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed