Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50037705
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50367916(Metribolone | R-1881 | METHYLTRIENOLONE)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185197(11-methyl-6,11-dihydro-5H-pyrido[3,2-a]carbazol-8-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185206(11-methyl-6,11-dihydro-5H-benzo[a]carbazol-9-ol | ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185194(11-methyl-6,11-dihydro-5-thia-4,11-diaza-benzo[a]f...)
Affinity DataIC50: 52nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185207(2-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185210(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-8-o...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185191(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-9-o...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185202(3,10-dimethyl-3,4,5,10-tetrahydropyrrolo[3,2-a]car...)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185190(10-methyl-5,10-dihydro-4H-thieno[3,2-a]carbazol-7-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185209(3-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50: 630nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 850nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185201(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-8-y...)
Affinity DataIC50: 880nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185213(12-methyl-5,6,7,12-tetrahydro-benzo[6,7]cyclohepta...)
Affinity DataIC50: 920nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185199(11-methyl-6,11-dihydro-5H-pyrido[4,3-a]carbazol-8-...)
Affinity DataIC50: 930nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185212(1-(8-hydroxythiochromeno[4,3-b]indol-11(6H)-yl)eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185193(8-chloro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185211(11-methyl-6,11-dihydrothiochromeno[4,3-b]indole-3,...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185192(11-ethyl-6,11-dihydrothiochromeno[4,3-b]indol-8-ol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185208(3-bromo-11-methyl-6,11-dihydrothiochromeno[4,3-b]i...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185204(8-fluoro-11-methyl-3-(trifluoromethyl)-6,11-dihydr...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185195(3-methoxy-11-methyl-6,11-dihydrothiochromeno[4,3-b...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185198(6,6,11-trimethyl-6,11-dihydrothiochromeno[4,3-b]in...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185205(8-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185200(3-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185203(6,11-dihydrothiochromeno[4,3-b]indol-8-ol | CHEMBL...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185189(12-methyl-6,7-dihydro-12H-5-thia-12-aza-dibenzo[a,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed