Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50017695
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185376((S)-benzo[b]thiophen-2-yl(2-(pyrrolidin-1-ylmethyl...)
Affinity DataKi:  4nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185383((S)-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)(5-(...)
Affinity DataKi:  4nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185371((S)-(5-chlorobenzofuran-2-yl)(2-(pyrrolidin-1-ylme...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185378((S)-2-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carb...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185370((S)-(2-(piperidin-1-ylmethyl)pyrrolidin-1-yl)(5-(t...)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185382((S)-(7-ethoxybenzofuran-2-yl)(2-(pyrrolidin-1-ylme...)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185377((S)-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)(5-(...)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185381((S)-(3-chlorobenzo[b]thiophen-2-yl)(2-(pyrrolidin-...)
Affinity DataKi:  12nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185372((S)-(2-((diethylamino)methyl)pyrrolidin-1-yl)(5-(t...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185380((S)-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)(6-(...)
Affinity DataKi:  15nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185375((S)-(2-(piperidin-1-ylmethyl)pyrrolidin-1-yl)(6-(t...)
Affinity DataKi:  22nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185374((S)-(2-((diethylamino)methyl)pyrrolidin-1-yl)(6-(t...)
Affinity DataKi:  46nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185373((S)-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)(qui...)
Affinity DataKi: >150nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50185379((S)-(2-(piperidin-1-ylmethyl)pyrrolidin-1-yl)(quin...)
Affinity DataKi: >150nMAssay Description:Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed