Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50000570
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(CHEMBL1788131 | CHEMBL325238 | 4-Phenyl-1-(4-pheny...)
Affinity DataKi:  0.800nMAssay Description:The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007396(CHEMBL112474 | 4-Phenyl-1-(5-phenyl-pentyl)-piperi...)
Affinity DataKi:  0.900nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007393(CHEMBL112124 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataKi:  1.10nMAssay Description:The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataKi:  2.60nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007409(CHEMBL112574 | 1-Naphthalen-2-yl-4-(3-phenyl-propy...)
Affinity DataKi:  2.80nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007410(CHEMBL112125 | 1-(4-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  2.90nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007398(CHEMBL115508 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataKi:  3nMAssay Description:The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataKi:  4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007395(CHEMBL420302 | 4-(4-Chloro-phenyl)-1-(4-phenyl-but...)
Affinity DataKi:  4.10nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007399(CHEMBL114477 | 1-(4-Phenyl-butyl)-4-(3-trifluorome...)
Affinity DataKi:  5.40nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 5.5nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007392(CHEMBL111896 | 1-Phenyl-4-(3-phenyl-propyl)-pipera...)
Affinity DataKi:  6.70nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007405(CHEMBL113293 | 1-Phenethyl-4-(3-trifluoromethyl-ph...)
Affinity DataKi:  7.5nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  10nMAssay Description:The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007404(CHEMBL113621 | 1-(3-Chloro-phenyl)-4-phenethyl-pip...)
Affinity DataKi:  11nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  19nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007402(CHEMBL114510 | 1-Phenyl-4-propyl-piperazine | 1-Ph...)
Affinity DataKi:  74nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007413(CHEMBL19351 | Phenyl-[4-(4-phenyl-butyl)-piperazin...)
Affinity DataKi:  125nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 160nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(CHEMBL1788131 | CHEMBL325238 | 4-Phenyl-1-(4-pheny...)
Affinity DataIC50: 165nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007396(CHEMBL112474 | 4-Phenyl-1-(5-phenyl-pentyl)-piperi...)
Affinity DataIC50: 210nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007393(CHEMBL112124 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 335nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 337nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007411(CHEMBL278509 | 1-Naphthalen-2-yl-piperazine)
Affinity DataKi:  550nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataKi:  1.15E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007398(CHEMBL115508 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 1.25E+3nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007406(TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...)
Affinity DataKi:  1.34E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi:  1.98E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007407(CHEMBL277120 | 1-NP | 1-Naphthalen-1-yl-piperazine...)
Affinity DataKi:  2.72E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 2.82E+3nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001913(4-METHOXYPHENYLPIPERAZINE | CHEMBL59517 | 1-(4-Met...)
Affinity DataKi:  5.85E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  6.15E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007400(CHEMBL1788131 | CHEMBL325238 | 4-Phenyl-1-(4-pheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007396(CHEMBL112474 | 4-Phenyl-1-(5-phenyl-pentyl)-piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007393(CHEMBL112124 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007403(1-PP | CHEMBL724 | 2-Piperazin-1-Yl-Pyrimidine | 1...)
Affinity DataKi: >1.00E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007393(CHEMBL112124 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007398(CHEMBL115508 | 4-Phenyl-1-(3-phenyl-propyl)-piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007396(CHEMBL112474 | 4-Phenyl-1-(5-phenyl-pentyl)-piperi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50004308(1-Benzoylpiperazine | 1-Benzyl-piperazine, 10 | 1-...)
Affinity DataKi:  1.05E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001862(CHEMBL9666 | 2-METHOXYPHENYLPIPERAZINE | 4-(2-Meth...)
Affinity DataKi:  1.12E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50004323(CHEMBL113624 | Phenyl-piperazin-1-yl-methanone)
Affinity DataKi:  1.14E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001898(CHEMBL9434 | 1-Phenyl-piperazine | PHENYLPIPERAZIN...)
Affinity DataKi:  1.14E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007394(CHEMBL334036 | 4-(2-Methoxy-phenyl)-piperidin-4-ol)
Affinity DataKi:  1.43E+4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed