Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50000572
TargetMu-type opioid receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 1.60nMAssay Description:Opioid receptor activity in terms of inhibition of [3H]dihydromorphine binding in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 4.20nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 6.10nMAssay Description:Opioid activity in terms of inhibition of [3H]dihydromorphine binding to opioid receptor mu in rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 9.5nMAssay Description:Opioid activity in terms of inhibition of [3H]dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 43nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding to dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: 54nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007420(CHEMBL418289 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 147nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 302nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007420(CHEMBL418289 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50: 1.79E+3nMAssay Description:Opioid activity in terms of inhibition of [3H]dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 3.05E+3nMAssay Description:Neuroleptic activity in terms of [3H]spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)