Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50017891
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 1nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 1nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 4nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188000(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188000(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 7nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 8nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 13nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 16nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 18nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 21nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 22nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 24nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 28nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 28nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 39nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 50nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 68nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188006(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 75nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 79nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187993(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 97nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187993(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188006(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187998(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 225nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187998(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 385nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: 415nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...)
Affinity DataIC50: 730nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188008(1-(4-((4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)met...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188005(1-(4-((4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)met...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188007(1-(5-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)furan-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188003(1-(5-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)furan-...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187994(3-(4-(5,7-dimethylbenzo[d]oxazol-2-ylamino)phenyl)...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188001(3-(4-aminophenyl)isothiazolo[5,4-d]pyrimidin-4-ami...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188004(N-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188009(3-(4-(5,7-dimethylbenzo[d]oxazol-2-ylamino)phenyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187999(3-(4-nitrophenyl)isothiazolo[5,4-d]pyrimidin-4-ami...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed