Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50018040
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 330nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 340nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 380nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 440nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-(4-amino-2-methylsulfanyl-phenylazo)benzenesulfo...)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 8.89E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190333(2-[(phenylcarbamoyl)oxy]-4-[(E)-2-(4-sulfamoylphen...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190338(2-({[4-(propan-2-yl)phenyl]carbamoyl}oxy)-4-[(E)-2...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190334(4-((3,4-dihydroxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190339(4-((4-methoxyphenyl)diazenyl)benzenesulfonamide | ...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190332(4-((4-hydroxy-3-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-(4-amino-2-methylsulfanyl-phenylazo)benzenesulfo...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-(4-amino-2-methylsulfanyl-phenylazo)benzenesulfo...)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190338(2-({[4-(propan-2-yl)phenyl]carbamoyl}oxy)-4-[(E)-2...)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-(4-amino-2-methylsulfanyl-phenylazo)benzenesulfo...)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190333(2-[(phenylcarbamoyl)oxy]-4-[(E)-2-(4-sulfamoylphen...)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190334(4-((3,4-dihydroxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190340(4-((3-hydroxy-4-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50: 6.64E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 8.45E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190339(4-((4-methoxyphenyl)diazenyl)benzenesulfonamide | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190332(4-((4-hydroxy-3-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM33266(p-Phenyldiazenyl derivative, 5 | CHEMBL379206 | az...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed