Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50037731
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190684((R)-3'-(3-methyl-2-oxo-2,3-dihydro-1,3-benzothiazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190695((R)-3'-(quinolin-6-yl)spiro[1-azabicyclo[2.2.2]oct...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190698((R)-3'-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190696((2S)-3'-(5-bromothien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410988(CHEMBL2113241)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410986(CHEMBL2113242)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410993(CHEMBL2113240)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410992(CHEMBL2113239)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410988(CHEMBL2113241)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50393256(CHEMBL2113232)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410991(CHEMBL2113236)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410990(CHEMBL2113228)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410989(CHEMBL2113233)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50410987(CHEMBL2113238)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190686((R)-3'-(2,3-dimethylbenzo[b]thiophen-5-yl)spiro[1-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190677((R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190696((2S)-3'-(5-bromothien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190686((R)-3'-(2,3-dimethylbenzo[b]thiophen-5-yl)spiro[1-...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190677((R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabi...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190687((R)-3'-(indan-5-yl)spiro[-1-azabicyclo[2.2.2]octan...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed