Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50018070
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190785(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190793(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]thieno[3,2-c]p...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190791(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]thieno[2,3-c]p...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190789(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  12.5nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190784(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2,3-dihydro-1...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190790(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[3,2-c]pyr...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190794(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]indoline-5-car...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]MLA from alpha-7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190785(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataKi:  174nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190785(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataKi:  188nMAssay Description:Activity at 5HT3 receptor expressed in SHEP1 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  310nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataKi:  511nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  580nMAssay Description:Activity at 5HT3 receptor expressed in SHEP1 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataKi:  628nMAssay Description:Activity at 5HT3 receptor expressed in SHEP1 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  663nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataKi:  962nMAssay Description:Activity at 5HT3 receptor expressed in SHEP1 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataKi:  1.66E+3nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataKi:  4.54E+3nMAssay Description:Activity at 5HT3 receptor expressed in SHEP1 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190785(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of alpha-3-beta-4 nAChR expressed in SHSY5Y cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of alpha-1-beta-1-gamma-delta nAChR expressed in TE671cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of alpha-3-beta-4 nAChR expressed in SHSY5Y cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of alpha-3-beta-4 nAChR expressed in SHSY5Y cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-1-beta-1-gamma-delta nAChR expressed in TE671cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-1-beta-1-gamma-delta nAChR expressed in TE671cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190788(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-3-beta-4 nAChR expressed in SHSY5Y cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-3-beta-4 nAChR expressed in SHSY5Y cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190785(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothioph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-1-beta-1-gamma-delta nAChR expressed in TE671cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50190783(N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-1-beta-1-gamma-delta nAChR expressed in TE671cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed