Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50032122
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324676((R)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  18nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of SEW2871-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324676((R)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  77nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of S1P-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324677((S)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  2.84E+3nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of SEW2871-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324677((S)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  4.63E+3nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of S1P-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed