Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50018234
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193221((3S,4S)-methyl 4-(4-(2-iodovinyl)phenyl)-1-methylp...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193217((3S,4S)-methyl 4-(4-(furan-2-yl)phenyl)-1-methylpi...)
Affinity DataKi:  18.5nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193216((3S,4S)-methyl 1-methyl-4-(4-(thiophen-3-yl)phenyl...)
Affinity DataKi:  31.8nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193219((3S,4S)-methyl 1-methyl-4-(4-(thiophen-2-yl)phenyl...)
Affinity DataKi:  90.8nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193221((3S,4S)-methyl 4-(4-(2-iodovinyl)phenyl)-1-methylp...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  167nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193217((3S,4S)-methyl 4-(4-(furan-2-yl)phenyl)-1-methylpi...)
Affinity DataKi:  205nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193216((3S,4S)-methyl 1-methyl-4-(4-(thiophen-3-yl)phenyl...)
Affinity DataKi:  598nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193218((3S,4S)-methyl 4-(4-formylphenyl)-1-methylpiperidi...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193216((3S,4S)-methyl 1-methyl-4-(4-(thiophen-3-yl)phenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193215((3S,4S)-methyl 1-methyl-4-(4-(thiazol-2-yl)phenyl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193218((3S,4S)-methyl 4-(4-formylphenyl)-1-methylpiperidi...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193215((3S,4S)-methyl 1-methyl-4-(4-(thiazol-2-yl)phenyl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193215((3S,4S)-methyl 1-methyl-4-(4-(thiazol-2-yl)phenyl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193218((3S,4S)-methyl 4-(4-formylphenyl)-1-methylpiperidi...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193221((3S,4S)-methyl 4-(4-(2-iodovinyl)phenyl)-1-methylp...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193215((3S,4S)-methyl 1-methyl-4-(4-(thiazol-2-yl)phenyl)...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193215((3S,4S)-methyl 1-methyl-4-(4-(thiazol-2-yl)phenyl)...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193219((3S,4S)-methyl 1-methyl-4-(4-(thiophen-2-yl)phenyl...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193217((3S,4S)-methyl 4-(4-(furan-2-yl)phenyl)-1-methylpi...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed