Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1739
LigandPNGBDBM13809((2S)-N-[(1S)-1-carbamoyl-2-[4-(1,1,3-trioxo-2,3-di...)
Affinity DataIC50: 65nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13808((2S)-N-[(1S)-1-carbamoyl-2-[4-(1,1,3-trioxo-1,2-th...)
Affinity DataIC50: 185nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13465((2S)-N-[(1S)-1-carbamoyl-2-{4-[(5S)-1,1,3-trioxo-1...)
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13807(Saturated (R, S)-IZD | (2S)-N-[(1S)-1-carbamoyl-2-...)
Affinity DataIC50: 210nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13806(5-(3-hydroxyphenyl)-2,3-dihydro-1,2-thiazole-1,1,3...)
Affinity DataIC50: 1.35E+3nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13472(DFMP 5 | ({4-[(2S)-2-carbamoyl-2-[(2S)-2-acetamido...)
Affinity DataIC50: 1.75E+3nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13811((2S)-N-[(1S)-1-carbamoyl-2-[4-(1,1,3-trioxo-2,3-di...)
Affinity DataIC50: 3.00E+3nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed
LigandPNGBDBM13812((2S)-N-[(1S)-1-carbamoyl-2-{4-[(5R)-1,1,3-trioxo-1...)
Affinity DataIC50: 1.60E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2007
Entry Details Article
PubMed