Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50018275
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193786(4-[4-(5-cyano-pyridin-2-yloxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193786(4-[4-(5-cyano-pyridin-2-yloxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193798(6-((1-cycloheptyl-5-oxopyrrolidin-3-yl)methoxy)nic...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193787(4-[3,3-dmethyl-2-oxo-4-(5-trifluoromethyl-pyridin-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193787(4-[3,3-dmethyl-2-oxo-4-(5-trifluoromethyl-pyridin-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193784(4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193789(4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193797(4-(3-benzyl-2-oxo-pyrrolidin-1-yl)-adamantane-1-ca...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193784(4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193789(4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phe...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193789(4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phe...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193786(4-[4-(5-cyano-pyridin-2-yloxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193793(6-(((3R,4R)-1-cycloheptyl-4-methyl-5-oxopyrrolidin...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193791(4-[3,3-dimethyl-2-oxo-4-(5-trifluoromethyl-pyridin...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50: 62nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193799(1-(2-adamantyl)-3-benzylpyrrolidin-2-one | CHEMBL2...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193793(6-(((3R,4R)-1-cycloheptyl-4-methyl-5-oxopyrrolidin...)
Affinity DataIC50: 75nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193784(4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193798(6-((1-cycloheptyl-5-oxopyrrolidin-3-yl)methoxy)nic...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193792(3-benzyl-1-cyclohexylpyrrolidin-2-one | CHEMBL2182...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193791(4-[3,3-dimethyl-2-oxo-4-(5-trifluoromethyl-pyridin...)
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193787(4-[3,3-dmethyl-2-oxo-4-(5-trifluoromethyl-pyridin-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 430nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193788((3s,9s)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193783((1R,7S,8r)-ethyl 4-(4-((5-cyanopyridin-2-yloxy)met...)
Affinity DataIC50: 518nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193794(3-benzyl-1-(5-hydroxy-adamantan-2-yl)-pyrrolidin-2...)
Affinity DataIC50: 832nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193789(4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phe...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193784(4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193789(4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phe...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193791(4-[3,3-dimethyl-2-oxo-4-(5-trifluoromethyl-pyridin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193794(3-benzyl-1-(5-hydroxy-adamantan-2-yl)-pyrrolidin-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193792(3-benzyl-1-cyclohexylpyrrolidin-2-one | CHEMBL2182...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193786(4-[4-(5-cyano-pyridin-2-yloxymethyl)-3,3-dimethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193799(1-(2-adamantyl)-3-benzylpyrrolidin-2-one | CHEMBL2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193787(4-[3,3-dmethyl-2-oxo-4-(5-trifluoromethyl-pyridin-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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