Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50037757
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 13.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid | CHEMBL377960)
Affinity DataIC50: 39.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid | CHEMBL378082)
Affinity DataIC50: 53.9nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid | CHEMBL21217...)
Affinity DataIC50: 62.5nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid | CHEMBL386309)
Affinity DataIC50: 375nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid | CHEMBL386309)
Affinity DataIC50: 9.05E+3nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid | CHEMBL377960)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid | CHEMBL21217...)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid | CHEMBL378082)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid | CHEMBL378082)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid | CHEMBL21217...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid | CHEMBL377960)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid | CHEMBL378082)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid | CHEMBL386309)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid | CHEMBL21217...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid | CHEMBL377960)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid | CHEMBL386309)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194245(2-(2-(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)prop...)
Affinity DataKi:  1.38nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194245(2-(2-(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)prop...)
Affinity DataKi:  529nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed