Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50037786
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of HDAC3 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC2 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC3 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195119((S)-N-(biphenyl-3-yl)-2-(2-(5-methoxy-2-methyl-1H-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195129((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195118((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195111((S)-N-(1-(3-methoxyphenylamino)-1,8-dioxononan-2-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 44nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195135((S)-N-(3-chlorophenyl)-2-(2-(5-methoxy-2-methyl-1H...)
Affinity DataIC50: 44nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC6 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195130((S)-N-(1-(biphenyl-3-ylamino)-1,8-dioxononan-2-yl)...)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195116(N-((S)-1-(biphenyl-3-ylamino)-1,8-dioxononan-2-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195120((S)-N-(1-(3-chlorophenylamino)-1,8-dioxononan-2-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195113((S)-methyl 7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 170nMAssay Description:Inhibition of HDAC2 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195128((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195107((S)-8-oxo-N-(2-(2-phenyl-1H-indol-3-yl)ethyl)-2-(2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC8 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195117(N-((S)-1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195132(N-((S)-1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195115((S)-7-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195123((S)-N-(4-chlorophenyl)-2-(2-(5-methoxy-2-methyl-1H...)
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC4 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195127((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 350nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195131((S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 480nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195125(N-((S)-1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 540nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195122((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 560nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195134((S)-N-(1,8-dioxo-1-(2-(2-phenyl-1H-indol-3-yl)ethy...)
Affinity DataIC50: 590nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195121((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 590nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195110((S)-2-acetamido-8-oxo-N-(2-(2-phenyl-1H-indol-3-yl...)
Affinity DataIC50: 930nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195112((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HDAC5 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HDAC5 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25144((2S)-2-[(1-methylpiperidin-2-yl)formamido]-8-oxo-N...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC8 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195124((R)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195133((S)-N-(2-chlorophenyl)-2-(2-(5-methoxy-2-methyl-1H...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195108((S)-N8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HDAC7 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195126((S)-8-hydroxy-2-(2-(5-methoxy-2-methyl-1H-indol-3-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195114((S)-N-ethyl-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195109((S)-2-(2-(5-methoxy-2-methyl-1H-indol-3-yl)acetami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed