Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50037865
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196700(N-[1-(3-nitrobenzyl)-3-piperidyl]-N-(1H-5-indazoly...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196694(N-(1-(thiophen-3-ylmethyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196718(N-(1-(thiophen-2-ylmethyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196692(N-(1-(4-methylbenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196711(1-benzyl-3-piperidyl-(1H-5-indazolyl)ether | 5-(1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196695(N-(1-(3,4-difluorobenzyl)piperidin-3-yl)-1H-indazo...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196690(N-(1-(4-aminobenzyl)piperidin-3-yl)-1H-indazol-5-a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196682(N-(1-(4-chlorobenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196689(N-[1-(1H-2-pyrrolylmethyl)-3-piperidyl]-N-(1H-5-in...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196707(N-[1-(2-chlorobenzyl)-3-piperidyl]-N-(1H-5-indazol...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196712(N-(1-(4-methoxybenzyl)piperidin-3-yl)-1H-indazol-5...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196704(1-benzyl-N-(1H-indazol-5-yl)piperidine-3-carboxami...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196728(N-[1-(3-chlorobenzyl)-3-piperidyl]-N-(1H-5-indazol...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196698(N-[1-(3-chlorobenzyl)-3-pyrrolidyl]-N-(1H-5-indazo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196725(N-(1-benzylpiperidin-3-yl)-1H-indazol-5-amine | N-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196725(N-(1-benzylpiperidin-3-yl)-1H-indazol-5-amine | N-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196687(1-(2,6-dichlorophenyl)-3-(3H-indazol-5-yl)urea | 1...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196686(N-[1-(4-chlorobenzyl)-3-pyrrolidyl]-N-(1H-5-indazo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196688(N-(1-(4-fluorobenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196708(N-(1-benzylpyrrolidin-3-yl)-1H-indazol-5-amine | N...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196699(N-[1-(3-aminobenzyl)-3-piperidyl]-N-(1H-5-indazoly...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196679(N-[1-(2-chlorobenzyl)-3-pyrrolidyl]-N-(1H-5-indazo...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196706(N-(1-(furan-2-ylmethyl)piperidin-3-yl)-1H-indazol-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196683(N-[1-(3-pyridylmethyl)-3-piperidyl]-N-(1H-5-indazo...)
Affinity DataIC50: 72nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196685(N-(1-(3,5-dimethoxybenzyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196681(N-(2,6-difluorobenzyl)-N0-(1H-5-indazolyl)urea | 1...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196702(N-[1-(2-aminobenzyl)-3-piperidyl]-N-(1H-5-indazoly...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196691(N-(1-(4-nitrobenzyl)piperidin-3-yl)-1H-indazol-5-a...)
Affinity DataIC50: 87nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196696(1-benzyl-4-piperidyl-(1H-5-indazolyl)ether | 5-(1-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196684(1-benzyl-N-(1H-5-indazolyl)piperidine-4-carboxamid...)
Affinity DataIC50: 136nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM107898(CHEMBL373487 | US8604218, 1.049)
Affinity DataIC50: 150nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196720(N-[1-(3-furylmethyl)-3-piperidyl]-N-(1H-5-indazoly...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196701(N-(1-(pyridin-4-ylmethyl)piperidin-3-yl)-1H-indazo...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196709(N-(2,4-dichlorobenzyl)-N0-(1H-5-indazolyl)urea | 1...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196680(N-(1-benzylpiperidin-4-yl)-1H-indazol-5-amine | N-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196721(N-(1-(pyridin-2-ylmethyl)piperidin-3-yl)-1H-indazo...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196697(1-benzyl-3-(1H-indazol-5-yl)urea | N-benzyl-N0-(1H...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196719(N-[1-(3-chlorobenzyl)-4-piperidyl]-N-(1H-5-indazol...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196723(N-[1-(4-chlorobenzyl)-4-piperidyl]-N-(1H-5-indazol...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196716(N1-benzyl-N4-(1H-5-indazolyl)-1,4-cyclohexanediami...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196722(N-(1-isobutylpiperidin-3-yl)-1H-indazol-5-amine | ...)
Affinity DataIC50: 340nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196727(N-[1-(2-chlorobenzyl)-4-piperidyl]-N-(1H-5-indazol...)
Affinity DataIC50: 440nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196715(N1-benzyl-N4-(1H-5-indazolyl)-1,4-cyclohexanediami...)
Affinity DataIC50: 520nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196705(N5-(1-benzyl-4-piperidyl)-1H-5-indazolecarboxyamid...)
Affinity DataIC50: 540nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196703(N-(1-ethylpiperidin-3-yl)-1H-indazol-5-amine | N-(...)
Affinity DataIC50: 780nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196711(1-benzyl-3-piperidyl-(1H-5-indazolyl)ether | 5-(1-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196694(N-(1-(thiophen-3-ylmethyl)piperidin-3-yl)-1H-indaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196682(N-(1-(4-chlorobenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196704(1-benzyl-N-(1H-indazol-5-yl)piperidine-3-carboxami...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
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