Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 1616
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12656((1S,6R)-3-{[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4...)
Affinity DataKi:  1.30nM ΔG°:  -50.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12654((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...)
Affinity DataKi:  3.60nM ΔG°:  -47.7kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  4.70nM ΔG°:  -47.1kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12653((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12652((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12651(1-{[trans-5-Amino-4-(2,4-dichlorophenyl)cyclohex-1...)
Affinity DataKi:  45nM ΔG°:  -41.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12652((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...)
Affinity DataKi:  73nM ΔG°:  -40.3kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12650((1S,6R)-6-(2-chlorophenyl)-3-phenylcyclohex-3-en-1...)
Affinity DataKi: <140nM ΔG°: <-38.7kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12653((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...)
Affinity DataKi:  230nM ΔG°:  -37.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12652((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...)
Affinity DataKi:  310nM ΔG°:  -36.8kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12654((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...)
Affinity DataKi:  430nM ΔG°:  -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12653((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12654((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...)
Affinity DataKi:  560nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12649((1S,6R)-6-(2-chlorophenyl)cyclohex-3-en-1-amine | ...)
Affinity DataKi:  820nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12656((1S,6R)-3-{[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4...)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  8.80E+3nM ΔG°:  -28.6kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12655((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...)
Affinity DataKi:  1.40E+4nM ΔG°:  -27.4kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12656((1S,6R)-3-{[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4...)
Affinity DataKi: >3.00E+4nM ΔG°: >-25.6kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed