Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50003822
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476261(CHEMBL224093 | 4-(1-Methylpyridinium)Phenylmethane...)
Affinity DataEC50:  3.16E+4nMAssay Description:Decrease in [3H]5-HT uptake at human SERT W103C mutant transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476262(CHEMBL224476)
Affinity DataEC50:  3.16E+3nMAssay Description:Decrease in [3H]5-HT uptake at human SERT G498C mutant transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476262(CHEMBL224476)
Affinity DataEC50:  2.00E+5nMAssay Description:Decrease in [3H]5-HT uptake at human SERT W103C mutant transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476261(CHEMBL224093 | 4-(1-Methylpyridinium)Phenylmethane...)
Affinity DataEC50:  3.98E+3nMAssay Description:Decrease in [3H]5-HT uptake at human SERT G498C mutant transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM81945(NSC_39484 | CHEMBL105891 | CHEMBL271379 | CHEMBL10...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of [3H]5-HT uptake at human SERT C109A mutant transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476261(CHEMBL224093 | 4-(1-Methylpyridinium)Phenylmethane...)
Affinity DataKi:  1.30E+6nMAssay Description:Inhibition of [3H]5-HT uptake at human SERT C109A mutant transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed