Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50018738
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198569((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198560((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-thiophen-3-yl-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198564((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-pyridin-3-yl-2...)
Affinity DataIC50: 28nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198561((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-pyrimidin-5-yl...)
Affinity DataIC50: 53nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198562((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-thiophen-2-yl-...)
Affinity DataIC50: 57nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198566((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-m-tolyl-2,3,6,...)
Affinity DataIC50: 68nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198565((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-phenyl-2,3,6,7...)
Affinity DataIC50: 91nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198567((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-nitro-pheny...)
Affinity DataIC50: 122nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198563((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-chloro-phen...)
Affinity DataIC50: 134nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198570((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(3-chloro-phen...)
Affinity DataIC50: 141nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198568((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-butyl-pheny...)
Affinity DataIC50: 152nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198559((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-trifluorome...)
Affinity DataIC50: 377nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed