Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50018817
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199266(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-2-na...)
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199251(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-7,8-...)
Affinity DataIC50: 0.75nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199249(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-7,8...)
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199254(6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-1-b...)
Affinity DataIC50: 0.910nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199248(6-(4-methylphenyl)-3-[2-(pyrrolidin-1-ylmethyl)-1-...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199258(6-(4-chlorophenyl)-3-[1-methyl-2-(pyrrolidin-1-ylm...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199256(6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-5,...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199260(6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-1-...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199253(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-5,6...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199265(6-(4-chlorophenyl)-3-(2-{[(2R)-2-(methoxymethyl)py...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199252(6-(4-chlorophenyl)-3-[2-(piperidin-1-ylmethyl)-1-b...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199261(6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxypyrrolidin...)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199262(6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-7,...)
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199257(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-5,6,...)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199263(6-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199255(6-(4-chlorophenyl)-3-{2-[(4-phenylpiperidin-1-yl)m...)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199246(3-(2-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]methy...)
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199247(6-(4-chlorophenyl)-3-{2-[(4-methylpiperazin-1-yl)m...)
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199259(6-(4-chlorophenyl)-3-{2-[(4-phenylpiperazin-1-yl)m...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199267(6-(4-chlorophenyl)-3-[6-(hydroxymethyl)-2-naphthal...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199264(6-(4-chlorophenyl)-3-[2-(morpholin-4-ylmethyl)-1-b...)
Affinity DataIC50: 38nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199250(6-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-...)
Affinity DataIC50: 1.41E+3nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199243(6-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199245(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylcarbonyl)-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199244(6-(4-chlorophenyl)-3-(2-naphthalenyl)thieno[3,2-d]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed