Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 1651
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12983(N-{5-[(2R)-2-hydroxy-2-phenylacetyl]-1H,4H,5H,6H-p...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12982(CHEMBL385266 | N-{5-[(2R)-2-fluoro-2-phenylacetyl]...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12985(CHEMBL402548 | N-{5-[(2R)-2-methoxy-2-phenylacetyl...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12984(CHEMBL427787 | 4-(4-methylpiperazin-1-yl)-N-{5-[(2...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12110(5-N-(2,6-diethylphenyl)-3-N-[4-(4-methylpiperazin-...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12983(N-{5-[(2R)-2-hydroxy-2-phenylacetyl]-1H,4H,5H,6H-p...)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12107(CHEMBL516110 | 5-Amido-pyrrolopyrazole 3 | 4-(4-me...)
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12985(CHEMBL402548 | N-{5-[(2R)-2-methoxy-2-phenylacetyl...)
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12984(CHEMBL427787 | 4-(4-methylpiperazin-1-yl)-N-{5-[(2...)
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12109(CHEMBL190252 | 4-(4-methylpiperazin-1-yl)-N-[5-(2-...)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12982(CHEMBL385266 | N-{5-[(2R)-2-fluoro-2-phenylacetyl]...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12987(CHEMBL384575 | N-{5-[(2S)-2-methoxy-2-phenylacetyl...)
Affinity DataIC50: 354nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12986(CHEMBL217748 | 4-(4-methylpiperazin-1-yl)-N-{5-[(2...)
Affinity DataIC50: 452nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12987(CHEMBL384575 | N-{5-[(2S)-2-methoxy-2-phenylacetyl...)
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nerviano Medical Sciences

LigandPNGBDBM12986(CHEMBL217748 | 4-(4-methylpiperazin-1-yl)-N-{5-[(2...)
Affinity DataIC50: 1.21E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed