Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000624
TargetNeuromedin-K receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007962(CHEMBL81919 | pGlu6-Phe-NMePhe-Gly-Leu-Met-NH2)
Affinity DataEC50:  0.900nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007972(CHEMBL311917 | pGlu6-Phe-Phe8(psi)CH2O-Gly-Leu-Met...)
Affinity DataEC50:  13nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007963(CHEMBL441061 | pGlu6-Phe-Phe-Gly-Leu-Met-NH2)
Affinity DataEC50:  5nMAssay Description:Effective dose was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methyl ester.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007962(CHEMBL81919 | pGlu6-Phe-NMePhe-Gly-Leu-Met-NH2)
Affinity DataEC50:  600nMAssay Description:Effective dose was measured on NK1 receptors of guinea pig ileum for maximal contraction in the presence of 3*10e-7 M atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007972(CHEMBL311917 | pGlu6-Phe-Phe8(psi)CH2O-Gly-Leu-Met...)
Affinity DataEC50:  40nMAssay Description:Effective dose was measured on NK1 receptors of guinea pig ileum for maximal contraction in the presence of 3*10e-7 M atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007963(CHEMBL441061 | pGlu6-Phe-Phe-Gly-Leu-Met-NH2)
Affinity DataEC50:  2.20nMAssay Description:Effective dose was measured on NK1 receptors of guinea pig ileum for maximal contraction in the presence of 3*10e-7 M atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007965(CHEMBL312194 | Tyr(psi)CH2O-Gly-Gly-Phe-Leu-NH2 | ...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to opioid receptor mu was determined in rat brain using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to opioid receptor mu was determined in rat brain using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007965(CHEMBL312194 | Tyr(psi)CH2O-Gly-Gly-Phe-Leu-NH2 | ...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity to opioid receptor delta was determined in rat brain using [3H]DSTBULET as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  629nMAssay Description:Binding affinity to opioid receptor delta was determined in rat brain using [3H]DSTBULET as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007966(CHEMBL420022 | Tyr-Gly(psi)CH2O-Gly-PheLeu-NH2)
Affinity DataKi:  1.38E+3nMAssay Description:Binding affinity to opioid receptor mu was determined in rat brain using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50007966(CHEMBL420022 | Tyr-Gly(psi)CH2O-Gly-PheLeu-NH2)
Affinity DataKi:  9.20E+3nMAssay Description:Binding affinity to opioid receptor delta was determined in rat brain using [3H]DSTBULET as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed