Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018938
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ACAT1 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human ACAT2 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033728(Pent-4-enoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033739(Butyric acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033722(CHEMBL9416 | Isobutyric acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 7.04E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033728(Pent-4-enoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 7.14E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033739(Butyric acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50: 7.76E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 8.45E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 9.48E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200395((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200395((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed