Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50019080
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201454(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(pyr...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201465(3-amino-N-(diaminomethylene)-5-(2,5-dichlorophenyl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201443(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(dim...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201470(5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201447(5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201472(3-amino-5-(5-chloro-2-methoxyphenyl)-N-(diaminomet...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50292303(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-meth...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201446(5-(3-chlorophenyl)-N-(diaminomethylene)-3-methylfu...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201450(N-(diaminomethylene)-3-methyl-5-phenylfuran-2-carb...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201441(3-amino-N-(diaminomethylene)-5-(2,5-dimethylphenyl...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201461(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(met...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201440(3-amino-N-(diaminomethylene)-5-(5-fluoro-2-methoxy...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201462(N-(diaminomethylene)-3-(dimethylamino)-5-phenylfur...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201448(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(dimethy...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201460(N-(diaminomethylene)-5-(2,5-difluorophenyl)-3-meth...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201464(3-amino-N-(diaminomethylene)-5-(2-methoxyphenyl)fu...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201457(3-amino-5-(3-chlorophenyl)-N-(diaminomethylene)fur...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201466(5-(3-chlorophenyl)-N-(diaminomethylene)-3-ethylfur...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201459(3-amino-N-(diaminomethylene)-5-o-tolylfuran-2-carb...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201442(3-amino-N-(diaminomethylene)-5-(2,5-difluorophenyl...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201458(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(pip...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201444(3-amino-N-(diaminomethylene)-5-(3-fluorophenyl)fur...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201475(3-amino-N-(diaminomethylene)-5-m-tolylfuran-2-carb...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201463(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(methyla...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201453(N-(diaminomethylene)-3-(methylamino)-5-phenylfuran...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201476(3-amino-N-(diaminomethylene)-5-(2-fluorophenyl)fur...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201451(3-amino-N-(diaminomethylene)-5-phenylfuran-2-carbo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201474(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(1H-pyrr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201455(3-acetamido-5-(5-chloro-2-methoxyphenyl)-N-(diamin...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201467(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(pyrroli...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201469(5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201471(3-acetamido-N-(diaminomethylene)-5-(2,5-dichloroph...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201445(3-acetamido-N-(diaminomethylene)-5-phenylfuran-2-c...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201477(3-acetamido-5-(3-chlorophenyl)-N-(diaminomethylene...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201468(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(piperid...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201456(N-(diaminomethylene)-3-(N-methylacetamido)-5-pheny...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201449(N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(N-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201452(5-(3-chlorophenyl)-N-(diaminomethylene)-3-(N-methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50201473(5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed