Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50019127
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202078((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(5-(3-(trifl...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202082((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202064((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202067((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 16.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202073((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202079((3R,3aS,4S,4aR,7S,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202084((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202070((3R,3aS,4S,4aS,8R,8aS,9aR)-decahydro-8-hydroxy-3-m...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202074((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202066((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202076((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 38.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202065((3R,3aS,4S,4aS,8S,8aS,9aR)-decahydro-8-hydroxy-3-m...)
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202072((3R,3aS,4S,4aS,8aS,9aR)-8,8-difluoro-decahydro-3-m...)
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202083((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202063((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202077((3R,3aS,4S,4aR,8aR,9aR)-7,7-difluoro-decahydro-3-m...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202080((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202075((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 147nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202081((-)-(3R,3aS,4S,4aR,6R,8aS,9aR)-decahydro-6-hydroxy...)
Affinity DataIC50: 481nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202071((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 829nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202068((+)-(3R,3aS,4S,4aR,6S,8aS,9aR)-decahydro-6-hydroxy...)
Affinity DataIC50: 845nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202069((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataIC50: 1.37E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202073((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed