Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 1906
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14974(N-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14974(N-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)...)
Affinity DataIC50: 2nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14971(4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14995(N-(2-{[3-(dimethylamino)propyl](methyl)amino}-5-(t...)
Affinity DataIC50: 4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14971(4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}...)
Affinity DataIC50: 4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14984(N-(5-cyclohexyl-2-methoxyphenyl)-4-methyl-3-({3-[2...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM15001(N-(2-((3-(Dimethylamino)propyl)(methyl)amino)-5-is...)
Affinity DataIC50: 6nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14996(4-methyl-3-({3-[4-(methylamino)-1,3,5-triazin-2-yl...)
Affinity DataIC50: 10nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14983(4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM15002(N-(5-Cyclopropyl-2-((3-(dimethylamino)propyl)(meth...)
Affinity DataIC50: 13nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14985(N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(4-...)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM15000(N-(2-((3-(Dimethylamino)propyl)(methyl)amino)-5-(t...)
Affinity DataIC50: 30nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14991(4-chloro-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 30nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM15020(N-(4-phenoxyphenyl)-3-[(3-{4-[(3,4,5-trimethoxyphe...)
Affinity DataIC50: 38nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM15019(N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]p...)
Affinity DataIC50: 38nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14992(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 39nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14994(2-Fluoro-5-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 40nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14975(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14995(N-(2-{[3-(dimethylamino)propyl](methyl)amino}-5-(t...)
Affinity DataIC50: 46nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14999(2-Fluoro-5-(3-(4-(methylamino)-1,3,5-triazin-2-yl)...)
Affinity DataIC50: 53nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14975(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50: 58nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14998(N-(2-((3-(Dimethylamino)propyl)(methyl)amino)-5-(t...)
Affinity DataIC50: 59nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14977(4-Methyl-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)-N-(...)
Affinity DataIC50: 59nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14990(4-fluoro-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 62nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14986(N-(5-Cyclohexyl-2-methoxyphenyl)-4-methyl-3-(3-(2-...)
Affinity DataIC50: 62nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM15018(4-[2-(phenylamino)pyridin-3-yl]-N-(3,4,5-trimethox...)
Affinity DataIC50: 68nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14984(N-(5-cyclohexyl-2-methoxyphenyl)-4-methyl-3-({3-[2...)
Affinity DataIC50: 70nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM15020(N-(4-phenoxyphenyl)-3-[(3-{4-[(3,4,5-trimethoxyphe...)
Affinity DataIC50: 85nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14996(4-methyl-3-({3-[4-(methylamino)-1,3,5-triazin-2-yl...)
Affinity DataIC50: 97nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14989(3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}...)
Affinity DataIC50: 99nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14979(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50: 100nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14979(N-[2-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-3...)
Affinity DataIC50: 103nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14997(4-methyl-3-({3-[4-(methylamino)-1,3,5-triazin-2-yl...)
Affinity DataIC50: 108nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14977(4-Methyl-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)-N-(...)
Affinity DataIC50: 153nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14973(4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}...)
Affinity DataIC50: 177nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14976(4-methyl-N-[2-(piperidin-1-yl)-5-(trifluoromethyl)...)
Affinity DataIC50: 181nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14983(4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 310nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14980(4-Methyl-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)...)
Affinity DataIC50: 366nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14993(2-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 388nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14982(4-methyl-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)...)
Affinity DataIC50: 399nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14972(4-Methyl-N-phenyl-3-(3-(pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 435nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14992(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: 461nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14973(4-methyl-3-{[3-(pyrimidin-4-yl)pyridin-2-yl]amino}...)
Affinity DataIC50: 504nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14991(4-chloro-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 675nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14978(4-Methyl-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)-N-(...)
Affinity DataIC50: 705nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14972(4-Methyl-N-phenyl-3-(3-(pyrimidin-4-yl)pyridin-2-y...)
Affinity DataIC50: 1.22E+3nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14980(4-Methyl-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14990(4-fluoro-3-({3-[2-(methylamino)pyrimidin-4-yl]pyri...)
Affinity DataIC50: 2.00E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
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