Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 2363
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19744(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 0.00300nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19743(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[2-(...)
Affinity DataIC50: 0.00300nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19736(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(4-meth...)
Affinity DataIC50: 0.00300nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19737(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(3-meth...)
Affinity DataIC50: 0.00300nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19733(2-cyano-4-(cyclohexylamino)-N-[2-(3-methoxyphenyl)...)
Affinity DataIC50: 0.00900nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19731(2-cyano-4-(cyclohexylamino)-N-(2-phenylethyl)pyrim...)
Affinity DataIC50: 0.0100nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19740(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[3-(4-m...)
Affinity DataIC50: 0.0110nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19741(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...)
Affinity DataIC50: 0.0110nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19742(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(1-...)
Affinity DataIC50: 0.0130nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19732(2-cyano-4-(cyclohexylamino)-N-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 0.0220nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19739(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(4-m...)
Affinity DataIC50: 0.0250nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19745(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 0.0310nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19735(2-cyano-4-(cyclohexylamino)-N-{2-[4-(4-methylpiper...)
Affinity DataIC50: 0.0470nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19731(2-cyano-4-(cyclohexylamino)-N-(2-phenylethyl)pyrim...)
Affinity DataIC50: 0.130nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19732(2-cyano-4-(cyclohexylamino)-N-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 0.170nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19733(2-cyano-4-(cyclohexylamino)-N-[2-(3-methoxyphenyl)...)
Affinity DataIC50: 0.230nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19738(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(pyr...)
Affinity DataIC50: 0.300nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19733(2-cyano-4-(cyclohexylamino)-N-[2-(3-methoxyphenyl)...)
Affinity DataIC50: 0.310nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19741(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...)
Affinity DataIC50: 0.330nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19736(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(4-meth...)
Affinity DataIC50: 0.340nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19735(2-cyano-4-(cyclohexylamino)-N-{2-[4-(4-methylpiper...)
Affinity DataIC50: 0.450nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19735(2-cyano-4-(cyclohexylamino)-N-{2-[4-(4-methylpiper...)
Affinity DataIC50: 0.480nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19744(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 0.510nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19743(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[2-(...)
Affinity DataIC50: 0.520nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19745(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 0.580nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19744(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 0.680nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19732(2-cyano-4-(cyclohexylamino)-N-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 0.700nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19734(2-cyano-4-(cyclohexylamino)-N-{2-[4-(pyrrolidin-1-...)
Affinity DataIC50: 0.75nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19740(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[3-(4-m...)
Affinity DataIC50: 0.820nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19743(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[2-(...)
Affinity DataIC50: 0.900nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19737(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(3-meth...)
Affinity DataIC50: 0.900nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19731(2-cyano-4-(cyclohexylamino)-N-(2-phenylethyl)pyrim...)
Affinity DataIC50: 1.10nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19737(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(3-meth...)
Affinity DataIC50: 1.20nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19736(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-[2-(4-meth...)
Affinity DataIC50: 1.60nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19742(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(1-...)
Affinity DataIC50: 1.70nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19740(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[3-(4-m...)
Affinity DataIC50: 1.80nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19734(2-cyano-4-(cyclohexylamino)-N-{2-[4-(pyrrolidin-1-...)
Affinity DataIC50: 2.30nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19741(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...)
Affinity DataIC50: 2.5nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19745(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{3-[2-(...)
Affinity DataIC50: 2.60nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19739(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(4-m...)
Affinity DataIC50: 3.10nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19739(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(4-m...)
Affinity DataIC50: 3.90nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19734(2-cyano-4-(cyclohexylamino)-N-{2-[4-(pyrrolidin-1-...)
Affinity DataIC50: 5.10nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19746(CHEMBL363847 | Purine lead structure, 1 | 6-(cyclo...)
Affinity DataIC50: 6nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19742(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(1-...)
Affinity DataIC50: 10nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19738(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(pyr...)
Affinity DataIC50: 10nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19738(2-cyano-4-[(2,2-dimethylpropyl)amino]-N-{2-[4-(pyr...)
Affinity DataIC50: 10nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19746(CHEMBL363847 | Purine lead structure, 1 | 6-(cyclo...)
Affinity DataIC50: 89nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19748(2-(cyclohexylamino)pyrimidine-4-carbonitrile | 4-C...)
Affinity DataIC50: 120nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19746(CHEMBL363847 | Purine lead structure, 1 | 6-(cyclo...)
Affinity DataIC50: 150nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19749(4-(cyclohexylamino)pyrimidine-2-carbonitrile | 2-C...)
Affinity DataIC50: 170nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
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