Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 2167
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17720(2-(4-{2-[bis(propan-2-yl)amino]ethoxy}phenyl)-3-ph...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17723(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 20nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17717(2-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-3-phenyl-N-...)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 25nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17715(N-[(2S)-oxolan-2-ylmethyl]-2,3-diphenylfuro[2,3-b]...)
Affinity DataIC50: 26nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17717(2-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-3-phenyl-N-...)
Affinity DataIC50: 32nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17723(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 37nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17720(2-(4-{2-[bis(propan-2-yl)amino]ethoxy}phenyl)-3-ph...)
Affinity DataIC50: 44nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17718(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pyrr...)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17717(2-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-3-phenyl-N-...)
Affinity DataIC50: 57nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17720(2-(4-{2-[bis(propan-2-yl)amino]ethoxy}phenyl)-3-ph...)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 71nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17722(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 80nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 84nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17718(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pyrr...)
Affinity DataIC50: 110nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17715(N-[(2S)-oxolan-2-ylmethyl]-2,3-diphenylfuro[2,3-b]...)
Affinity DataIC50: 110nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 120nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17716(2,3-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b...)
Affinity DataIC50: 140nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17717(2-{4-[2-(morpholin-4-yl)ethoxy]phenyl}-3-phenyl-N-...)
Affinity DataIC50: 150nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17723(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17718(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pyrr...)
Affinity DataIC50: 170nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17720(2-(4-{2-[bis(propan-2-yl)amino]ethoxy}phenyl)-3-ph...)
Affinity DataIC50: 180nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17722(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 180nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17718(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pyrr...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17716(2,3-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17716(2,3-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b...)
Affinity DataIC50: 360nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17723(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 370nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17724(N-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-2-{4-[2-(p...)
Affinity DataIC50: 380nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17716(2,3-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b...)
Affinity DataIC50: 420nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17724(N-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-2-{4-[2-(p...)
Affinity DataIC50: 930nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17724(N-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-2-{4-[2-(p...)
Affinity DataIC50: 1.40E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17722(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17724(N-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-2-{4-[2-(p...)
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17715(N-[(2S)-oxolan-2-ylmethyl]-2,3-diphenylfuro[2,3-b]...)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17715(N-[(2S)-oxolan-2-ylmethyl]-2,3-diphenylfuro[2,3-b]...)
Affinity DataIC50: 4.20E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17722(3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-...)
Affinity DataIC50: 4.70E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed