Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50019709
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM14244(4,5-dibromo-3-(carboxymethoxy)thiophene-2-carboxyl...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207000(5-(4-bromo-5-phenylthien-3-yl)-1,2,5-thiadiazolidi...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207002(2-(2-allyl-4,5-dibromothiophen-3-yloxy)acetic acid...)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207011(2-(4,5-dibromo-2-(morpholine-4-carbonyl)thiophen-3...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207014(2-(4,5-dibromo-2-(2-hydroxyacetyl)thiophen-3-yloxy...)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206994(2-(4,5-dibromo-2-(2H-tetrazol-5-yl)thiophen-3-ylox...)
Affinity DataIC50: 4.30E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207010({[4,5-dibromo-2-(hydrazinocarbonyl)thien-3-yl]oxy}...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207006(2-(4,5-dibromo-2-cyanothiophen-3-yloxy)acetic acid...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207012(4,5-dibromo-3-(2,2,2-trifluoroethoxy)thiophene-2-c...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207004(3-((2H-tetrazol-5-yl)methoxy)-4,5-dibromothiophene...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207021(4,5-dibromo-3-(2,3-dihydroxypropoxy)thiophene-2-ca...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207020(3-(allyloxy)-4,5-dibromothiophene-2-carboxylic aci...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207019(2-(4,5-dibromo-2-(hydroxymethyl)thiophen-3-yloxy)a...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207015(2-(2-acetamido-4,5-dibromothiophen-3-yloxy)acetic ...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207001(2-(4,5-dibromo-2-(5-ethyl-1,2,4-oxadiazol-3-yl)thi...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206998(4,5-dibromo-3-(2-(hydroxyamino)-2-oxoethoxy)thioph...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206999(4,5-dibromo-3-(2-hydroxyethoxy)thiophene-2-carboxy...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207023(2-(4,5-dibromo-2-carbamoylthiophen-3-yloxy)acetic ...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206996(2-(4,5-dibromo-2-(thiazol-2-ylcarbamoyl)thiophen-3...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206993(2-(4,5-dibromothiophen-3-yloxy)acetic acid | CHEMB...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207017(2-(4,5-dibromo-2-(5-methyl-1,2,4-oxadiazol-3-yl)th...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206989(2-(2-((1H-pyrazol-5-yl)carbamoyl)-4,5-dibromothiop...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207018(4,5-dibromo-3-(cyanomethoxy)thiophene-2-carboxylic...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206986(2-(4,5-dibromo-2-(5-isopropyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206997({[5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PH...)
Affinity DataKi:  300nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206991(2-(5-(3-(1-(benzylsulfonyl)piperidin-4-yloxy)pheny...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207008(2-(4-bromo-5-(3-(3,3,5,5-tetramethylcyclohexylamin...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207009(N-{3-[3-chloro-4-(1,1,4-trioxo-1,2,5-thiadiazolidi...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206987(5-{4-methyl-5-[3-(1-phenylmethanesulfonyl-piperidi...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207003(2-(4-bromo-5-(3-(N-(3,3,5,5-tetramethylcyclohexyl)...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207024(5-{5-[3-(cyclohexylamino)phenyl]-4-methylthien-3-y...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206988(5-{4-chloro-5-[3-(cyclohexylamino)phenyl]thien-3-y...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206990(5-{4-methyl-5-[3-(3,3,5,5-tetramethyl-cyclohexylam...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207022(5-(4-chloro-5-phenylthien-3-yl)-1,2,5-thiadiazolid...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206995(5-(2,4-dichloro-5-phenylthien-3-yl)-1,2,5-thiadiaz...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM14244(4,5-dibromo-3-(carboxymethoxy)thiophene-2-carboxyl...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207000(5-(4-bromo-5-phenylthien-3-yl)-1,2,5-thiadiazolidi...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207016(2-(4-bromo-5-(3-(cyclohexylamino)phenyl)-2-(2H-tet...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207013(2-(4-bromo-5-phenyl-2-(2H-tetrazol-5-yl)thiophen-3...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207007(5-(4-methyl-5-phenylthien-3-yl)-1,2,5-thiadiazolid...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207005(2-(5-phenyl-2-(2H-tetrazol-5-yl)thiophen-3-yloxy)a...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206992(2-(4-methyl-5-phenyl-2-(2H-tetrazol-5-yl)thiophen-...)
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50207014(2-(4,5-dibromo-2-(2-hydroxyacetyl)thiophen-3-yloxy...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50206994(2-(4,5-dibromo-2-(2H-tetrazol-5-yl)thiophen-3-ylox...)
Affinity DataKi:  2.70E+5nMAssay Description:Inhibition of PTP1B assessed as pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed